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Symbol
Name
ID

Tdo2
tryptophan 2,3-dioxygenase
MGI:1928486

Phenotype annotations related to nervous system

Darker colors indicate more annotations

Human Phenotypes

Echolalia

Phonic tics

Stuttering

Depression

Emotional lability

Hypersexuality

Aggressive behavior

Compulsive behaviors

Motor tics

Attention deficit hyperactivity disorder

Self-mutilation

Intellectual disability

Intellectual disability, moderate

Sleep abnormality

Global developmental delay

Disease(s) Associated with TDO2

familial hypertryptophanemia

Gilles de la Tourette syndrome

Mouse Phenotypes		abnormal neuron differentiation	abnormal neuronal precursor proliferation	abnormal olfactory bulb development	small lateral ventricles	increased prepulse inhibition
Availability	Mouse Genotype	abnormal neuron differentiation	abnormal neuronal precursor proliferation	abnormal olfactory bulb development	small lateral ventricles	increased prepulse inhibition
	Tdo2^tm1Tnak/Tdo2^tm1Tnak
	Tdo2^{tm1b(KOMP)Mbp}/Tdo2⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23